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"Birch, Caitlin"
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Marley learns a lesson
When a pair of kittens joins the family, an exuberant Marley enjoys teaching his new friends all about life at the house, from where to wait for Cassie to where not to sniff, until a thunderstorm reveals helpful lessons that the kittens can teach.
Book
The stepwise process of integrating a genetic counsellor into primary care
Genetic services have historically been housed in tertiary care, requiring referral, which can present access barriers. While integrating genetics into primary care could facilitate access, many primary care physicians lack genomics expertise. Integrating genetic counsellors (GCs) into primary care could theoretically address these issues, but little is known about how to do this effectively. To understand and describe the process of integrating a GC into a multidisciplinary primary care setting, we qualitatively explored the perceptions, attitudes and reactions of existing team members prior to, and after the introduction of a GC. Semi-structured interviews were conducted immediately prior to (T1), and 9 months after (T2), the GC joining the clinic. Interviews were recorded, transcribed verbatim and analyzed concurrently with data collection using interpretive description. Twenty-four interviews were conducted with 17 participants (13 at T1, 11 at T2). Participants described several distinct, progressive stages of interaction with the GC: Disinterest or Resistance, Pre-Collaboration, Initial Collaboration, and Effective Collaboration/Integration of the GC into the team. At each stage, specific needs had to be met in order to advance to the next stage of collaboration. A variety of barriers and facilitators attended movement between different stages of the model. The Stepwise Process of Integration Model describes the process through which primary care staff and clinicians integrate a GC into their practice. The insight provided by this model could be used to facilitate more effective integration of GCs into other primary care settings.
Journal Article
On Pfiesteria, Scientific sleuths got their man; Skeptical researchers were persuaded by examining victims
When Dr. J. Glenn Morris Jr. gathered a team of medical sleuths to follow the trail of Pfiesteria piscicida, he suspected they were chasing a mirage. If it weren't for the work of [JoAnn] Burkholder, a 43-year-old aquatic ecologist, Pfiesteria might still be undiscovered. She stumbled on it in 1988, when a colleague at North Carolina State University asked her to help figure out what was killing the fish in a research aquarium. Burkholder and her colleagues suspected from the start that Pfiesteria was killing fish in the wild. But they couldn't prove it until May 1990, when a state chemist in North Carolina cruised into a mass of a million bleeding menhaden, southern flounder, hogchokers and spot, thrashing wildly in the coffee-colored water of the Pamlico River.
Newspaper Article
Search for CP violation in the phase space of D 0 → π−π+π 0 decays with the energy test
A search for CP violation in D-0 -> pi(-)pi(+)pi(0) decays is reported, using pp collision data collected by the LHCb experiment from 2015 to 2018 corresponding to an integrated luminosity of 6 fb(-1). An unbinned model-independent approach provides sensitivity to local CP violation within the two-dimensional phase space of the decay. The method is validated using the Cabibbo-favoured channel D-0 -> K-pi(+)pi(0) and background regions of the signal mode. The results are consistent with CP symmetry in this decay.
Journal Article
Observation of the B 0 s â D + D - decay
The first observation of the B-s(0) -> D*+ D*- decay and the measurement of its branching ratio relative to the B-0 -> D*+ D*(-) decay are presented. The data sample used corresponds to an integrated luminosity of 9 fb(-1) of proton-proton collisions recorded by the LHCb experiment at centre-of-mass energies of 7, 8 and 13 TeV between 2011 and 2018. The decay is observed with more than 10 standard deviations and the time-integrated ratio of branching fractions is determined to be [GRAPHICS] . where the first uncertainty is statistical, the second systematic and the third due to the uncertainty of the fragmentation fraction ratio f(s)/f(d). The B-s(0) -> D*(+) D*(-) branching fraction is calculated to be [GRAPHICS] . where the fourth uncertainty is due to the B-0 -> D*(+) D*(-) branching fraction. These results are calculated using the average B-s(0) meson lifetime in simulation. Correction factors are reported for scenarios where either a purely heavy or a purely light B-s(0) eigenstate is considered.
Journal Article
Study of $B^0_s \\to J\\psi \\pi^+\\pi^-K^+K^-$ decays
$\\to$The decays $ {\\mathrm{B}}_{\\mathrm{s}}^0 $ → J/ψπ$^+$π$^-$K$^+$K$^-$ are studied using a data set corresponding to an integrated luminosity of 9 fb$^{-1}$, collected with the $LHC$b detector in proton-proton collisions at centre-of-mass energies of $7$, $8$ and $13 TeV$. The decays $B_S^0$ $\\to$ $J/\\psi$ $K^{*0}\\overline{K}^{+0}$ and $B^0_S\\to_{Xcl}(3872)K^+K^-$, where the $K^+K^-$pair does not originate from a $\\phi$ meson, are observed for the first time. Precise measurements of the ratios of branching fractions between intermediate $_{Xcl}(3872)\\phi$, $J/{\\psi}K^{*0}\\overline{K}^{*0}$, $\\psi(2S)\\phi$ and $_{Xcl}(3872)K^+K^-$ states are reported. A structure, denoted as $X(4740)$, is observed in the $J/\\psi\\phi$ mass spectrum and, assuming a Breit-Wigner parameterisation, its mass and width are determined to be $$m_{X(4740)}=4741\\pm6\\pm6MeV/c^2,$$$\\Gamma_{X(4740)}=53\\pm15\\pm11MeV,$$where the first uncertainty is statistical and the second is systematic. In addition, the most precise single measurement of the mass of the $$m_{B^0_S}=5366.98\\pm0.07\\pm0.13MeV/c^2.$$
Journal Article
Measurement of the CKM angle $\\gamma$ and $B^0_s$-$\\bar{B}^0_s$ mixing frequency with $B^0_s \\rightarrow D_s^\\mp h^\\pm \\pi^\\pm \\pi^\\mp$ decays
The CKM angle γ is measured for the first time from mixing-induced CP violation between $ {B}_s^0\\to {D}_s^{\\mp }{K}^{\\pm }{\\pi}^{\\pm }{\\pi}^{\\mp } $ and $ {\\overline{B}}_s^0\\to {D}_s^{\\pm }{K}^{\\mp }{\\pi}^{\\mp }{\\pi}^{\\pm } $ decays reconstructed in proton-proton collision data corresponding to an integrated luminosity of 9 fb$^{−1}$ recorded with the LHCb detector. A time-dependent amplitude analysis is performed to extract the CP-violating weak phase γ − 2β$_{s}$ and, subsequently, γ by taking the $ {B}_s^0\\hbox{-} {\\overline{B}}_s^0 $ mixing phase β$_{s}$ as an external input. The measurement yields γ = (44 ± 12)° modulo 180°, where statistical and systematic uncertainties are combined. An alternative model-independent measurement, integrating over the five-dimensional phase space of the decay, yields $ \\gamma =\\left({44}_{-13}^{+20}\\right){}^{\\circ} $ modulo 180°. Moreover, the $ {B}_s^0\\hbox{-} {\\overline{B}}_s^0 $ oscillation frequency is measured from the flavour-specific control channel $ {B}_s^0\\to {D}_s^{-}{\\pi}^{+}{\\pi}^{+}{\\pi}^{-} $ to be ∆m$_{s}$ = (17.757 ± 0.007(stat) ± 0.008(syst)) ps$^{−1}$, consistent with and more precise than the current world-average value.[graphic not available: see fulltext]
Journal Article
Measurement of CP observables in $B^\\pm \\to D^{()} K^\\pm$ and $B^\\pm \\to D^{()} \\pi^\\pm$ decays using two-body $D$ final states
Measurements of CP observables in B$^{±}$ → D$^{(*)}$K$^{±}$ and B$^{±}$ → D$^{(*)}$π$^{±}$ decays are presented, where D$^{(∗)}$ indicates a neutral D or D$^{∗}$ meson that is an admixture of meson and anti-meson states. Decays of the D$^{(∗)}$ meson to the Dπ$^{0}$ and Dγ final states are partially reconstructed without inclusion of the neutral pion or photon. Decays of the D meson are reconstructed in the K$^{±}$π$^{∓}$, K$^{+}$K$^{−}$, and π$^{+}$π$^{−}$ final states. The analysis uses a sample of charged B mesons produced in proton-proton collisions and collected with the LHCb experiment, corresponding to integrated luminosities of 2.0, 1.0, and 5.7 fb$^{−1}$ taken at centre-of-mass energies of 7, 8, and 13 TeV, respectively. The measurements of partially reconstructed B$^{±}$ → D$^{(*)}$K$^{±}$ and B$^{±}$ → D$^{(∗)}$π$^{±}$ with D → K$^{∓}$π$^{±}$ decays are the first of their kind, and a first observation of the B$^{±}$ → $ {\\left(D{\\pi}^0\\right)}_{D^{\\ast }}{\\pi}^{\\pm } $ decay is made with a significance of 6.1 standard deviations. All CP observables are measured with world-best precision, and in combination with other LHCb results will provide strong constraints on the CKM angle γ.[graphic not available: see fulltext]
Journal Article